For US Healthcare Professionals

Explore PsA clinical manifestations in the hall of statues

Get to know the clinical manifestations of PsA

  • Sacroiliitis and spondylitis
  • Extra-musculoskeletal
  • Peripheral articular manifestations
  • Associated conditions

Important distinctions are emerging about which cytokines contribute to various clinical manifestations

Gaze upon the Gallery of Cytokines


Burden of disease

Examine the prevalence of comorbidities in patients with PsA, and the overall burden of disease.

Continue PsA tour Back to: Clinical features


Clinical features

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  2. Mease PJ, Armstrong AW. Managing patients with psoriatic disease: the diagnosis and pharmacologic treatment of psoriatic arthritis in patients with psoriasis. Drugs. 2014;74(4):423-441. doi:10.1007/s40265-014-0191-y
  3. Ogdie A, Weiss P. The epidemiology of psoriatic arthritis. Rheum Dis Clin North Am. 2015;41(4):545-568. doi:10.1016/j.rdc.2015.07.001
  4. Sobolewski P, Walecka I, Dopytalska K. Nail involvement in psoriatic arthritis. Rheumatologia. 2017;55(3):131-135. doi:10.5114/reum.2017.68912
  5. Prignano F, Ricceri F, Pescitelli L, et al. Itch in psoriasis: epidemiology, clinical aspects and treatment options. Clin Cosmet Investig Dermatol. 2009;2:9-13.doi: 10.2147/ccid.s4465
  6. Centers for Disease Control and Prevention. Psoriasis. Published August 18, 2020. Accessed March 21, 2022
  7. Kaeley GS, Eder L, Aydin SZ, et al. Dactylitis: A hallmark of psoriatic arthritis. Semin Arthritis Rheum. 2018;48(1):263-273.
  8. Helliwell PS, Firth J, Ibrahim GH, et al. Development of an assessment tool for dactylitis in patients with psoriatic arthritis. J Rheumatol. 2005;32(9):1745-1750.
  9. Lopez-Medina C, Molto A, Sieper J, et al. Prevalence and distribution of peripheral musculoskeletal manifestations in spondyloarthritis including psoriatic arthritis: results of the worldwide, cross-sectional ASAS-PerSpA study. RMD Open. 2021;7:e001450. Doi:10.1136/rmdopen-2020-001450.
  10. Kaeley GS, Eder L, Aydin SZ, Gutierrez M, et al. Enthesitis: A hallmark of psoriatic arthritis. Semin Arthritis Rheum. 2018;48(1):35-43. doi:10.1016/j.semarthrit.2017.12.008
  11. Belasco J, Wei N. Psoriatic arthritis: what is happening at the joint?. Rheumatol Ther. 2019;6(3):305-315. doi:10.1007/s40744-019-0159-1
  12. Felquer Acosta ML, FitzGerald O. Peripheral joint involvement in psoriatic arthritis patients. Clin Exp Rheumatol. 2015;33:S26-S30
  13. Mortezavi M, Thiele R, Ritchlin C. The joint in psoriatic arthritis. Clin Exp Rheumatol. 2015;33(5 Suppl 93):S20-S25
  14. Benavent D, Plasencia-Rodríguez C, Franco-Gómez K, et al. Axial spondyloarthritis and axial psoriatic arthritis: similar or different disease spectrum?. Ther Adv Musculoskelet Dis. 2020;12:1759720X20971889. Published 2020. doi:10.1177/1759720X20971889
  15. Fotiadou C, Lazaridou E. Psoriasis and uveitis: links and risks. Psoriasis (Auckl). 2019;9:91-96. Published 2019 Aug 28. doi:10.2147/PTT.S179182
  16. Guly CM, Forrester JV. Investigation and management of uveitis. BMJ. 2010;341:c4976. Published 2010. doi:10.1136/bmj.c4976
  17. Fraga NA, Oliveira Mde F, Follador I, et al. Psoriasis and uveitis: a literature review. An Bras Dermatol. 2012;87(6):877-883. doi:10.1590/s0365-05962012000600009
  18. Chia AYT, Ang GWX, Chan ASY, et al. Managing psoriatic arthritis with inflammatory bowel disease and/or uveitis. Front Med (Lausanne). 2021;8:737256. Published 2021. doi:10.3389/fmed.2021.737256
  19. Bergman JM, Zuegar P, Song J, et al. Inflammatory bowel disease is associated with a substantial economic burden in patients with psoriatic arthritis and in patients with ankylosing spondylitis (Abstract 285). 2018; ACR/ARHP Annual Meeting.